Article
Atg17 regulates the magnitude of the autophagic response.
Molecular biology of the cell - 1 Jul 2005
Cheong Heesun, Yorimitsu Tomohiro, Reggiori Fulvio, Legakis Julie E, Wang Chao-Wen, Klionsky Daniel J
Abstract excerpt
Autophagy is a catabolic process used by eukaryotic cells for the degradation and recycling of cytosolic proteins and excess or defective organelles. In yeast, autophagy is primarily a response to nutrient limitation, whereas in higher eukaryotes it also plays a role in developmental processes. Due to its essentially unlimited degradative capacity, it is critical that regulatory mechanisms are in place to...
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