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Article

Bi-allelic and tri-allelic 5-HTTLPR polymorphisms and triptan non-response in cluster headache.

The journal of headache and pain - 21 Jul 2014

Schürks Markus, Frahnow Antje, Diener Hans-Christoph, Kurth Tobias, Rosskopf Dieter, Grabe Hans-Jörgen

Abstract excerpt

BACKGROUND: Triptans are only effective in terminating cluster headache (CH) attacks in 70-80% of patients. Pharmacogenetic aspects of the serotonin metabolism, specifically variation in the 5-HTTLPR may be involved. METHODS: Genetic association study in a well-defined cohort of 148 CH patients with information on drug response to triptans. CH was diagnosed according to the criteria of the International Headache...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25043824
DOI: 10.1186/1129-2377-15-46
PMCID: PMC4112603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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