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Article

Genetic and Phenotypic Profiling of Triptan Users in a Swedish Cluster Headache Cohort.

Journal of molecular neuroscience : MN - 18 Apr 2024

Jennysdotter Olofsgård Felicia, Ran Caroline, Qin Yuyan, Fourier Carmen, Waldenlind Elisabet, Steinberg Anna, Sjöstrand Christina, Belin Andrea Carmine

Abstract excerpt

Up to 25% of individuals who live with cluster headache (CH), an extremely painful primary headache disorder, do not adequately respond to the first-line treatment, triptans. Studies have indicated that genetic variants can play a role in treatment response. Likewise, differences in clinical characteristics can give clues to mechanisms underlying triptan non-response. Our aim was to investigate five genetic...

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PMID: 38634984
DOI: 10.1007/s12031-024-02219-1
PMCID: PMC11026232

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