Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Negative predictors of clinical response to triptans in patients with migraine.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Apr 2012

Ishii M, Sakairi Y, Hara H, Imagawa A, Shimizu S, Takahashi J, Nagamine A, Naito Y, Masuda Y, Usami S, Kiuchi Y

Abstract excerpt

Moderate to severe migraine attacks are treated with triptans. However, about 25% of migraineurs fail to respond to triptans. We investigated the involvement of gene polymorphisms, personality traits and characteristics of headache, and made a scoring system for prediction of clinical response to triptans in patients with migraine. Gene polymorphisms including serotonin (5-HT)(1B) receptor G861C and dopamine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Migraine Disorders
Share to Personality

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Personality Inventory

Share to Receptors, Dopamine D2

Share to Receptors, Serotonin

Share to Serotonin Antagonists

Share to Serotonin Plasma Membrane Transport Proteins

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 21822697
DOI: 10.1007/s10072-011-0716-z

Genes

DRD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Negative predictors of clinical response to triptans in patients with migraine.PMID 21822697Read ↗

The serotonin transporter gene polymorphism STin2 VNTR confers an increased risk of inconsistent response to triptans in migraine patients.Semantic proximity Read ↗

Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine.Semantic proximity Read ↗

Clinical and genetic characterization of non-optimal triptan response among migraine patients.Semantic proximity Read ↗

G protein beta3 polymorphism and triptan response in cluster headache.Semantic proximity Read ↗

Predictive index for the onset of medication overuse headache in migraine patients.Semantic proximity Read ↗

The influence of genetic constitution on migraine drug responses.Semantic proximity Read ↗

Bi-allelic and tri-allelic 5-HTTLPR polymorphisms and triptan non-response in cluster headache.Semantic proximity Read ↗

Association between response to triptans and response to erenumab: real-life dataSemantic proximity Read ↗

Gene polymorphisms involved in triptans pharmacokinetics and pharmacodynamics in migraine therapy.Semantic proximity Read ↗

Association study between clinical response to rizatriptan and some candidate genes.Semantic proximity Read ↗

Genetic and Phenotypic Profiling of Triptan Users in a Swedish Cluster Headache Cohort.Semantic proximity Read ↗

Migraine polygenic risk score associates with efficacy of migraine-specific drugsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.