CRP 1846C>T Genetic Polymorphism Is Associated with Lymph Node Metastasis and/or Severe Lymphatic Invasion in Endometrial Cancer.

doi:10.1620/tjem.237.25

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Article

CRP 1846C>T Genetic Polymorphism Is Associated with Lymph Node Metastasis and/or Severe Lymphatic Invasion in Endometrial Cancer.

The Tohoku journal of experimental medicine - 1 Sept 2015

Kito Masahiko, Motoyama Satoru, Fujita Kazuma, Miura Masatomo, Nanjo Hiroshi, Sato Naoki, Shimizu Dai, Sato Toshiharu, Makino Kenichi, Sugawara Tae, Kato Aya, Tamura Daisuke, Takahashi Kazue, Kumazawa Yukiyo, Sato Wataru, Miura Hiroshi, Shirasawa Hiromitsu, Sato Akira, Kumagai Jin, Terada Yukihiro

Abstract excerpt

Endometrial cancer (EC) rates are rising in Japan. Lymph node (LN) metastasis is an important prognostic factor in EC, and its risk is increased with higher tumor grade, deep myometrial invasion, larger tumor size, and lymphovascular space invasion (LVSI). Current methodologies to assess these factors are unreliable. We previously showed the association between C-reactive protein (CRP) 1846C>T (rs1205)...

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PMID: 26310275
DOI: 10.1620/tjem.237.25

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