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Article

Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis.

International journal of cancer - 1 Mar 2015

Scholtysik René, Kreuz Markus, Hummel Michael, Rosolowski Maciej, Szczepanowski Monika, Klapper Wolfram, Loeffler Markus, Trümper Lorenz, Siebert Reiner, Küppers Ralf

Abstract excerpt

The pathogenesis of diffuse large B-cell lymphomas (DLBCL) is only partly understood. We analyzed 148 DLBCL by single nucleotide polymorphism (SNP)-chips to characterize genomic imbalances. Seventy-nine cases were of the germinal center B-cell like (GCB) type of DLBCL, 49 of the activated B-cell like (ABC) subtype and 20 were unclassified DLBCL. Twenty-four regions of recurrent genomic gains and 38 regions of...

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Share to DNA Copy Number Variations
Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genomics

Share to Loss of Heterozygosity

Share to Lymphoma, Large B-Cell, Diffuse

Share to Neoplasm Recurrence, Local

Share to Oligonucleotide Array Sequence Analysis

Source

Identifiers

PMID: 25042405
DOI: 10.1002/ijc.29072

Genes

BACH2
CASP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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