Article
Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma.
Allergy - 1 Sept 2014
Kupczyk M, Dahlén B, Sterk P J, Nizankowska-Mogilnicka E, Papi A, Bel E H, Chanez P, Howarth P H, Holgate S T, Brusselle G, Siafakas N M, Gjomarkaj M, Dahlén S-E
Abstract excerpt
BACKGROUND: Although asthma is characterized by variable airways obstruction, most studies of asthma phenotypes are cross-sectional. The stability of phenotypes defined either by biomarkers or by physiological variables was assessed by repeated measures over 1 year in the Pan-European BIOAIR cohort of adult asthmatics. METHODS: A total of 169 patients, 93 with severe asthma (SA) and 76 with mild-to-moderate...
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