Article
Ten-year follow-up of cluster-based asthma phenotypes in adults. A pooled analysis of three cohorts.
American journal of respiratory and critical care medicine - 1 Sept 2013
Boudier Anne, Curjuric Ivan, Basagaña Xavier, Hazgui Hana, Anto Josep M, Bousquet Jean, Bridevaux Pierre O, Dupuis-Lozeron Elise, Garcia-Aymerich Judith, Heinrich Joachim, Janson Christer, Künzli Nino, Leynaert Bénédicte, de Marco Roberto, Rochat Thierry, Schindler Christian, Varraso Raphaëlle, Pin Isabelle, Probst-Hensch Nicole, Sunyer Jordi, Kauffmann Francine, Siroux Valérie
Abstract excerpt
RATIONALE: The temporal stability of adult asthma phenotypes identified using clustering methods has never been addressed. Longitudinal cluster-based methods may provide novel insights in the study of the natural history of asthma. OBJECTIVES: To compare the stability of cluster-based asthma phenotype structures a decade apart in adults and to address the individuals' phenotypic transition across these asthma...
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