U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.

doi:10.1016/j.jaci.2016.08.048

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Article

U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.

The Journal of allergy and clinical immunology - 1 Jun 2017

Lefaudeux Diane, De Meulder Bertrand, Loza Matthew J, Peffer Nancy, Rowe Anthony, Baribaud Frédéric, Bansal Aruna T, Lutter Rene, Sousa Ana R, Corfield Julie, Pandis Ioannis, Bakke Per S, Caruso Massimo, Chanez Pascal, Dahlén Sven-Erik, Fleming Louise J, Fowler Stephen J, Horvath Ildiko, Krug Norbert, Montuschi Paolo, Sanak Marek, Sandstrom Thomas, Shaw Dominic E, Singer Florian, Sterk Peter J, Roberts Graham, Adcock Ian M, Djukanovic Ratko, Auffray Charles, Chung Kian Fan

Abstract excerpt

BACKGROUND: Asthma is a heterogeneous disease in which there is a differential response to asthma treatments. This heterogeneity needs to be evaluated so that a personalized management approach can be provided. OBJECTIVES: We stratified patients with moderate-to-severe asthma based on clinicophysiologic parameters and performed an omics analysis of sputum. METHODS: Partition-around-medoids clustering was applied...

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PMID: 27773852
DOI: 10.1016/j.jaci.2016.08.048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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