Article
Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study.
Respiratory research - 15 Dec 2016
Loza Matthew J, Djukanovic Ratko, Chung Kian Fan, Horowitz Daniel, Ma Keying, Branigan Patrick, Barnathan Elliot S, Susulic Vedrana S, Silkoff Philip E, Sterk Peter J, Baribaud Frédéric
Abstract excerpt
BACKGROUND: Asthma is a disease of varying severity and differing disease mechanisms. To date, studies aimed at stratifying asthma into clinically useful phenotypes have produced a number of phenotypes that have yet to be assessed for stability and to be validated in independent cohorts. The aim of this study was to define and validate, for the first time ever, clinically driven asthma phenotypes using two...
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