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Article

DNA methyltransferase haplotype is associated with Alzheimer's disease.

Neuroscience letters - 5 Sept 2014

Pezzi Julio Carlos, Ens Cintia Monique Boschmann, Borba Ericksen Mielle, Schumacher-Schuh Artur F, de Andrade Fabiana Michelsen, Chaves Marcia Lorena Fagundes, Fiegenbaum Marilu, Camozzato Ana Luiza

Abstract excerpt

Epigenetic mechanisms have been implicated in syndromes associated with neuropsychiatric disorders, but little is known about the role of epigenetics in Alzheimer's disease (AD). DNA methylation, one of the main epigenetic mechanisms, is a complex process carried out by specific enzymes, such as DNMT1 and DNMT3B. This study aimed to investigate the association between DNMT1 and DNMT3B polymorphisms and AD. Two...

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Source

Identifiers

PMID: 25038421
DOI: 10.1016/j.neulet.2014.07.013

Genes

DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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