Article
Association between DNA methyltransferase gene polymorphism and Parkinson's disease.
Neuroscience letters - 3 Feb 2017
Pezzi Julio Carlos, de Bem Cintia Monique Boschmann Ens, da Rocha Tatiane Jacobsen, Schumacher-Schuh Artur F, Chaves Marcia Lorena Fagundes, Rieder Carlos Roberto, Hutz Mara H, Fiegenbaum Marilu, Camozzato Ana Luiza
Abstract excerpt
Parkinson's disease (PD) is a common and complex neurodegenerative disorder, the second most prevalent, only behind Alzheimer's disease. Recent studies suggest that environmental factors may contribute for neurodegeneration through induction of epigenetic modifications, such as DNA methylation, that is carried out by enzymes, such as DNMT1 and DNMT3B. This present study targeted to investigate the association...
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