Article
Impact of IL28B on the treatment decision in naïve and experienced patients with genotype 1 and 4 chronic hepatitis C in real-life clinical practice: a prospective multicenter cohort.
Clinics and research in hepatology and gastroenterology - 1 Dec 2014
Halfon Philippe, Ouzan Denis, Asselah Tarik, Renou Christophe, Allègre Thierry, Delasalle Patrick, Lafeuillade Alain, Cadranel Jean-François, Haddad Nabil, Khiri Hacène, Pénaranda Guillaume, Bourlière Marc
Abstract excerpt
BACKGROUND: The impact of the IL28B genotype on the real-life treatment decisions for patients infected with the hepatitis C virus (HCV) is unknown. OBJECTIVE: To prospectively analyze the impact of IL28B genotype in HCV genotype 1 (G1)- or 4 (G4)-infected patients using buccal epithelial cell samples in real-life clinical practices. PATIENTS AND METHODS: From October 2011 to March 2013, 1007 CHC patients were...
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