Article
IL28B in the era of direct-acting antivirals for hepatitis C.
Journal of clinical gastroenterology - 1 Mar 2013
Muir Andrew J
Abstract excerpt
The IL28B genotype is the strongest baseline predictor of hepatitis C treatment response with peginterferon-α and ribavirin. In 2011, 2 protease inhibitors were approved for genotype 1 infection in combination with peginterferon-α and ribavirin, and boceprevir and telaprevir attenuate the association between the IL28B genotype and treatment response. Although sustained virologic response rates are improved for...
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