Article
Impact of IL28B genotype on first-week response to telaprevir-based therapy in HIV-HCV coinfection.
Antiviral therapy - 1 Jan 2015
Neukam Karin, Munteanu Daniela, Haubitz Sebastian, Mira José A, Ingiliz Patrick, Rivero-Juárez Antonio, Lutz Thomas, de los Santos-Gil Ignacio, Scholten Stefan, Márquez Manuel, Rauch Andri, Rockstroh Jürgen K, Pineda Juan A
Abstract excerpt
BACKGROUND: IL28B genotype predicts response to treatment against HCV with pegylated interferon/ribavirin (PR) and impacts on the outcome of therapy including telaprevir (TVR). This study aimed to determine the influence of the favourable IL28B genotype on early viral kinetics during therapy with TVR/PR in HIV-HCV-coinfected patients. METHODS: All HIV-HCV genotype 1 coinfected subjects who received TVR/PR for at...
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