Article
Sequence variation analysis of the E1 and E2 genes of human papillomavirus type 16 in cervical lesions in women from the south of Poland.
Acta biochimica Polonica - 28 Apr 2021
Sitarz Katarzyna, Kopec Jolanta, Zawilinska Barbara, Klimek Malgorzata, Szostek Slawa
Abstract excerpt
The E1 and E2 genes of the human papillomavirus encode the so-called early proteins, their sequences are conserved, and regulatory functions are associated with the viral oncoproteins. The purpose of this study is to determine the HPV16 E1 and E2 mutations appearing in the female population of southern Poland, depending on the severity of cervical pathological changes. We also take into account the number of E1...
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