Article
Functional implication of sequence variation in the long control region and E2 gene among human papillomavirus type 18 variants.
Archives of virology - 1 Jan 2009
López-Saavedra Alejandro, González-Maya Leticia, Ponce-de-León Sergio, García-Carrancá Alejandro, Mohar Alejandro, Lizano Marcela
Abstract excerpt
Cervical cancer incidence remains highly frequent in developing countries. It is possible that populations of these countries are exposed to more oncogenic human papillomavirus (HPV) variants. Functional differences among high-risk HPV variants have been described, suggesting repercussions on their oncogenic potential. In this report, we demonstrate that the long control region (LCR) of HPV18 variants has...
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