Article
Strong mutator phenotype drives faster adaptation from growth on glucose to growth on acetate in Salmonella.
Microbiology (Reading, England) - 1 Oct 2014
Le Bars Hervé, Bonnaure-Mallet Martine, Barloy-Hubler Frédérique, Jolivet-Gougeon Anne, Bousarghin Latifa
Abstract excerpt
The metabolic adaptation of strong mutator strains was studied to better understand the link between the strong mutator phenotype and virulence. Analysis of the growth curves of isogenic strains of Salmonella, which were previously grown in M63 glucose media, revealed that the exponential phase of growth was reached earlier in an M63 acetate medium with strong mutator strains (mutated in mutS or in mutL) than...
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