Article
[Detection and significance of epidermal growth factor receptor mutation in esophageal, esophagogastric junction and gastric cancers].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 May 2014
Lyu Xiao, Huang Jing, Liu Jian, Wang Wenna, Su Yiqun, Zhang Wen, Sun Yongkun, Ying Jianming, Wang Jinwan, Sun Yan
Abstract excerpt
OBJECTIVE: Tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) have been reported to be effective in the treatment of esophageal and esophagogastric junction cancers. The aim of this study was to detect the frequency of EGFR mutation and expression in Chinese patients with esophageal, esophagogastric junction and gastric cancers, and to clarify the value of EGFR mutation and...
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