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Aberrant DNA methylation patterns in diabetic nephropathy

24 Jun 2014

Abstract excerpt

BACKGROUND: The aim of this study was to evaluate whether global levels of DNA methylation status were associated with albuminuria and progression of diabetic nephropathy in a case-control study of 123 patients with type 2 diabetes- 53 patients with albuminuria and 70 patients without albuminuria. METHODS: The 5-methyl cytosine content was assessed by reverse phase high pressure liquid chromatography (RP-HPLC) of...

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PMID: 25028646
DOI: 10.1186/2251-6581-13-69

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