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Genetics and Epigenetics of Diabetic Nephropathy

1 Jan 2015

Abstract excerpt

BACKGROUND: Diabetic nephropathy (DN) is the most common cause of end-stage renal disease (ESRD) in the USA and worldwide, contributing to significant morbidity and mortality in diabetic patients. A genetic factor for the development of DN is strongly implicated, as only one third of diabetic patients eventually develop kidney disease. Growing evidence also supports an important role of epigenetic modifications...

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Share to Chronic Kidney Disease and Diabetes
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PMID: 27536664
DOI: 10.1159/000381796

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