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DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy.

Epigenetics - 1 Jan 2011

Sapienza Carmen, Lee Jean, Powell Jasmine, Erinle Oluwatoyin, Yafai Faahud, Reichert James, Siraj Elias S, Madaio Michael

Abstract excerpt

We identified potential epigenetic biomarkers for chronic kidney disease progression by comparing site-specific DNA methylation levels in more than 14,000 genes between African American and Hispanic diabetes patients with end stage renal disease (ESRD) and diabetes patients without nephropathy. We identified 187 genes that are differentially methylated between the two groups on at least two CpG sites in each gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21150313
DOI: 10.4161/epi.6.1.13362

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