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Article

Global DNA methylation as a possible biomarker for diabetic retinopathy

28 Jul 2014

Abstract excerpt

BACKGROUND: We evaluated whether global levels of DNA methylation status were associated with retinopathy as well as providing a predictive role of DNA methylation in developing retinopathy in a case-control study of 168 patients with type 2 diabetes. METHODS: The 5-methylcytosine content was assessed by reversed-phase high-pressure liquid chromatography of peripheral blood leukocytes to determine an individual's...

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PMID: 25069700
DOI: 10.1002/dmrr.2584

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