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Article

Intercellular network structure and regulatory motifs in the human hematopoietic system

1 Jul 2014

Abstract excerpt

The hematopoietic system is a distributed tissue that consists of functionally distinct cell types continuously produced through hematopoietic stem cell (HSC) differentiation. Combining genomic and phenotypic data with high-content experiments, we have built a directional cell-cell communication network between 12 cell types isolated from human umbilical cord blood. Network structure analysis revealed that ligand...

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Share to Hematopoietic Stem Cell Transplantation
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PMID: 25028490
DOI: 10.15252/msb.20145141

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