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A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data

8 Jan 2019

Abstract excerpt

Abstract Recent advances in single-cell molecular analytical methods and clonal growth assays are enabling more refined models of human hematopoietic lineage restriction processes to be conceptualized. Here, we report the results of integrating single-cell proteome measurements with clonally determined lymphoid, neutrophilic/monocytic, and/or erythroid progeny outputs from >1000 index-sorted CD34+ human cord...

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PMID: 30622121
DOI: 10.1182/blood-2018-10-878025

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