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Toxoplasma gondii Ingests and Digests Host Cytosolic Proteins

16 Jul 2014

Abstract excerpt

The protozoan parasite Toxoplasma gondii resides within a nonfusogenic vacuole during intracellular replication. Although the limiting membrane of this vacuole provides a protective barrier to acidification and degradation by lysosomal hydrolases, it also physically segregates the parasite from the host cytosol. Accordingly, it has been suggested that T. gondii acquires material from the host via membrane...

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PMID: 25028423
DOI: 10.1128/mbio.01188-14

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