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Article

Molecular Dissection of Novel Trafficking and Processing of the T oxoplasma gondii Rhoptry Metalloprotease Toxolysin‐1

28 Oct 2011

Abstract excerpt

Toxoplasma gondii utilizes specialized secretory organelles called rhoptries to invade and hijack its host cell. Many rhoptry proteins are proteolytically processed at a highly conserved SΦXE site to remove organellar targeting sequences that may also affect protein activity. We have studied the trafficking and biogenesis of a secreted rhoptry metalloprotease with homology to insulysin that we named toxolysin-1...

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Identifiers

PMID: 22035499
DOI: 10.1111/j.1600-0854.2011.01308.x

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