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Toxoplasma, or the discovery of a heterophage.

Trends in parasitology - 1 Oct 2014

Coppens Isabelle

Abstract excerpt

In mammalian cells, the protozoan pathogen Toxoplasma resides in a nonfusiogenic vacuole that segregates it from host cell resources. How the parasite acquires nutrients and whether it is capable of internalizing host macromolecules have been long-standing mysteries. By exploiting a mutant of Toxoplasma lacking the cathepsin protease L, Dou et al. observed the accumulation of host cytosolic-derived proteins in a...

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PMID: 25178740
DOI: 10.1016/j.pt.2014.08.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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