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An ortholog of <i>P. falciparum</i> chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in <i>Toxoplasma gondii</i> to facilitate host invasion

2018-09-06

Abstract excerpt

Toxoplasma gondii is an apicomplexan parasite with the ability to use foodborne, zoonotic, and congenital routes of transmission that causes severe disease in immunocompromised patients. The parasites harbor a lysosome-like digestive vacuole, termed the “Vacuolar Compartment/Plant-Like Vacuole” (VAC/PLV), which plays an important role in maintaining the lytic cycle and virulence of T. gondii . The VAC supplies pr...

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Literature Corpus work
8d660900-6306-5851-8598-4c32a852baf4
DOI
10.1101/409904
Open publication

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