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Article

Somatic signature of brain-specific single nucleotide variations in sporadic Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2014

Parcerisas Antoni, Rubio Sara E, Muhaisen Ashraf, Gómez-Ramos Alberto, Pujadas Lluís, Puiggros Montserrat, Rossi Daniela, Ureña Jesús, Burgaya Ferrán, Pascual Marta, Torrents David, Rábano Alberto, Avila Jesús, Soriano Eduardo

Abstract excerpt

BACKGROUND: Although genome-wide association studies have shown that genetic factors increase the risk of suffering late-onset, sporadic Alzheimer's disease (SAD), the molecular mechanisms responsible remain largely unknown. OBJECTIVE: The aim of the study was to investigate the presence of somatic, brain-specific single nucleotide variations (SNV) in the hippocampus of SAD samples. METHODS: By using...

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Source

Identifiers

PMID: 25024348
DOI: 10.3233/JAD-140891

Genes

CSMD1
LRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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