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Article

Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry

29 Mar 2019

Abstract excerpt

Importance: Some of the unexplained heritability of Alzheimer disease (AD) may be due to rare variants whose effects are not captured in genome-wide association studies because very large samples are needed to observe statistically significant associations. Objective: To identify genetic variants associated with AD risk using a nonstatistical approach. Design, Setting, and Participants: Genetic association study...

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PMID: 30924900
DOI: 10.1001/jamanetworkopen.2019.1350

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