Article
Genetics of canine anal furunculosis in the German shepherd dog.
Immunogenetics - 1 May 2014
Massey Jonathan, Short Andrea D, Catchpole Brian, House Arthur, Day Michael J, Lohi Hannes, Ollier William E R, Kennedy Lorna J
Abstract excerpt
Canine anal furunculosis (AF) is characterised by ulceration and fistulation of perianal tissue and is a disease that particularly affects German shepherd dogs (GSDs). There are some similarities between AF and perianal Crohn's disease (CD) in man. An immune-mediated aetiopathogenesis for AF has been suggested due to tissue pathology, a major histocompatibility complex (MHC) association and clinical response to...
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