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Article

A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation.

The American journal of cardiology - 15 Aug 2014

Kolek Matthew J, Edwards Todd L, Muhammad Raafia, Balouch Adnan, Shoemaker M Benjamin, Blair Marcia A, Kor Kaylen C, Takahashi Atsushi, Kubo Michiaki, Roden Dan M, Tanaka Toshihiro, Darbar Dawood

Abstract excerpt

For many patients with atrial fibrillation, ventricular rate control with atrioventricular (AV) nodal blockers is considered first-line therapy, although response to treatment is highly variable. Using an extreme phenotype of failure of rate control necessitating AV nodal ablation and pacemaker implantation, we conducted a genome-wide association study (GWAS) to identify genomic modulators of rate control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25015694
DOI: 10.1016/j.amjcard.2014.05.040
PMCID: PMC4119836

Genes

SOX5
CDCP1
IGFBP7
LANCL2
SAMD5
SASH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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