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Article

Ki67 antigen contributes to the timely accumulation of protein phosphatase 1γ on anaphase chromosomes.

The Journal of biological chemistry - 15 Aug 2014

Takagi Masatoshi, Nishiyama Yuko, Taguchi Atsuko, Imamoto Naoko

Abstract excerpt

Ki67 is a protein widely used as cell-proliferation marker, with its cellular functions being hardly unveiled. In this paper, we present the direct interaction between Ki67 and PP1γ, a protein phosphatase showing characteristic accumulation on anaphase chromosomes via the canonical PP1-binding motif within Ki67. In cells depleted of Ki67, PP1γ is targeted to anaphase chromosomes less efficiently. Additionally,...

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Identifiers

PMID: 25012651
DOI: 10.1074/jbc.M114.556647
PMCID: PMC4132790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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