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Article

The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1.

Oncotarget - 30 Mar 2015

Ritter Andreas, Sanhaji Mourad, Steinhäuser Kerstin, Roth Susanne, Louwen Frank, Yuan Juping

Abstract excerpt

The mitotic centromere-associated kinesin (MCAK), a potent microtubule depolymerase, is involved in regulating microtubule dynamics. The activity and subcellular localization of MCAK are tightly regulated by key mitotic kinases, such as Polo-like kinase 1 (Plk1) by phosphorylating multiple residu...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25504441
DOI: 10.18632/oncotarget.2843
PMCID: PMC4466640

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25504441-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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