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Article

Mitotic phosphorylation of MPP8 by cyclin-dependent kinases regulates chromatin dissociation.

Biochemical and biophysical research communications - 22 Mar 2013

Nishigaki Makoto, Kawada Yu, Misaki Toshinori, Murata Kazuhiro, Goshima Takahiro, Hirokawa Takahisa, Yamada Chisato, Shimada Midori, Nakanishi Makoto

Abstract excerpt

Repressive epigenetic modifications, DNA methylation at CpG sites and histone H3 lysine 9 (H3K9) methylation, are enriched in heterochromatin, which undergoes drastic changes in structure during mitosis. MPP8 (M phase phosphoprotein 8) has been proposed to regulate positive association between these two repressive modifications, but actual involvement of this protein in changes in the heterochromatin structure...

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Identifiers

PMID: 23416073
DOI: 10.1016/j.bbrc.2013.02.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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