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Article

Rapid evolution of BRCA1 and BRCA2 in humans and other primates.

BMC evolutionary biology - 11 Jul 2014

Lou Dianne I, McBee Ross M, Le Uyen Q, Stone Anne C, Wilkerson Gregory K, Demogines Ann M, Sawyer Sara L

Abstract excerpt

BACKGROUND: The maintenance of chromosomal integrity is an essential task of every living organism and cellular repair mechanisms exist to guard against insults to DNA. Given the importance of this process, it is expected that DNA repair proteins would be evolutionarily conserved, exhibiting very...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25011685
DOI: 10.1186/1471-2148-14-155
PMCID: PMC4106182

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25011685-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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