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Bioinformatics Approaches to Explore the Phylogeny and Role of BRCA1 in Breast Cancer.

Critical reviews in eukaryotic gene expression - 1 Jan 2000

Jabbir Farwa, Irfan Muhammad, Mustafa Ghulam, Ahmad Hafiz Ishfaq

Abstract excerpt

BRCA1 and BRCA2 are the two major vulnerability genes involved in hereditary breast cancer. BRCA1 gene programs for a tumor suppressor protein that helps in repairing DNA. The purpose of this study was to reveal the position and nature of amino acid residues involved in breast cancer, and it provides a complete characterization of BRCA1 and its evolutionary relationship with 34 selected organisms. The sequences...

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Identifiers

PMID: 32422010
DOI: 10.1615/CritRevEukaryotGeneExpr.2019030785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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