Article
HS1,2 Ig enhancer alleles association to AIDS progression in a pediatric cohort infected with a monophyletic HIV-strain.
BioMed research international - 1 Jan 2014
Montesano Carla, Giambra Vincenzo, Frezza Domenico, Palma Paolo, Serone Eliseo, Gattinara Guido Castelli, Mattei Maurizio, Mancino Giorgio, Colizzi Vittorio, Amicosante Massimo
Abstract excerpt
Alteration in the humoral immune response has been observed during HIV infection. The polymorphisms of enhancer HS1,2, member of the 3(') regulatory region of the Ig heavy chain cluster, may play a role in the variation of the humoral response leading to pathological conditions. To assess the rol...
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