Article
Virologic and immunologic markers of disease progression in pediatric HIV infection.
AIDS research and human retroviruses - 1 Sept 1996
Viganò A, Balotta C, Trabattoni D, Salvaggio A, Riva C, Bricalli D, Crupi L, Colombo M C, Principi N, Galli M, Clerici M
Abstract excerpt
Correlates of progression of human immunodeficiency virus (HIV) infection to AIDS include the reduction in CD4+ T cells and the emergence of syncytium-inducing (SI) HIV variants. It has been suggested that progressive defects in interleukin 2 (IL-2), IL-12, and IFN- gamma production (type 1 cytokines), and increased production of IL-4 (and of IL-4-driven hyper-IgE), IL-6, and IL-10 (type 2 cytokines), could...
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