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Article

Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing.

Nature communications - 10 Jul 2014

Uchida Shusaku, Martel Guillaume, Pavlowsky Alice, Takizawa Shuichi, Hevi Charles, Watanabe Yoshifumi, Kandel Eric R, Alarcon Juan Marcos, Shumyatsky Gleb P

Abstract excerpt

Changes in the stability of microtubules regulate many biological processes, but their role in memory remains unclear. Here we show that learning causes biphasic changes in the microtubule-associated network in the hippocampus. In the early phase, stathmin is dephosphorylated, enhancing its micro...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25007915
DOI: 10.1038/ncomms5389
PMCID: PMC4137320

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25007915-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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