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Article

TRP14 inhibits osteoclast differentiation via its catalytic activity.

Molecular and cellular biology - 15 Sept 2014

Hong Sohyun, Huh Jeong-Eun, Lee Soo Young, Shim Jae-Kyung, Rhee Sue Goo, Jeong Woojin

Abstract excerpt

We previously reported the inhibitory role of thioredoxin-related protein of 14 kDa (TRP14), a novel disulfide reductase, in nuclear factor-κB (NF-κB) activation, but its biological function has remained to be explored. Here, we evaluated the role of TRP14 in the differentiation and function of osteoclasts (OCs), for which NF-κB and cellular redox regulation have been known to be crucial, using RAW 264.7...

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Identifiers

PMID: 25002534
DOI: 10.1128/MCB.00293-14
PMCID: PMC4135626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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