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Article

Characterization of the NF-kappaB activation induced by TR8, an osteoclastogenic tumor necrosis factor receptor family member.

Archives of pharmacal research - 1 Oct 1999

Kim H H

Abstract excerpt

TR8 is a recently identified member of the tumor necrosis factor (TNF) receptor superfamily. TR8 seems to play important roles in bone metabolism as stimulation of this receptor with its ligand, TL8 or osteoclast differentiation factor (ODF), induced the differentiation and activation of osteoclasts. Despite its important biological functions, the biochemical events ensuing from TR8 activation have not been...

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Share to Membrane Glycoproteins
Share to NF-kappa B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Serine-Threonine Kinases

Share to RANK Ligand

Share to Receptor Activator of Nuclear Factor-kappa B

Share to Receptors, Tumor Necrosis Factor

Share to TNF Receptor-Associated Factor 6

Source

Identifiers

PMID: 10549571
DOI: 10.1007/BF02979152

Genes

TNF
TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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