Article
Elevated postinjury thrombospondin 1-CD47 triggering aids differentiation of patients' defective inflammatory CD1a+dendritic cells.
Journal of leukocyte biology - 1 Nov 2014
Bandyopadhyay Gautam, Bandyopadhyay Sanjukta, Bankey Paul E, Miller-Graziano Carol L
Abstract excerpt
A subset of Pts develops dysfunctional MO to inflammatory DC differentiation and immunosuppression. MDDC, a newly described DC subset, is pivotal in initiating antibacterial responses. Endogenous proteins are known to alter MO to MDDC differentiation. In particular, trauma-elevated TSP-1, a prote...
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