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Article

Exosomes derived from LPS-stimulated human thymic mesenchymal stromal cells enhance inflammation via thrombospondin-1.

Bioscience reports - 29 Oct 2021

Li Qianru, Li Jing, Sun Lei, Sun Yun, Zhao Fei, Liu Pingping, Peng Xin, Xuan Xiaoyan, Li Yun, Wang Peng, Tan Chen, Du Ying

Abstract excerpt

Inflammatory response mediated by immune cells is either directly or indirectly regulated by mesenchymal stromal cells (MSCs). Accumulating evidence suggests that thrombospondin-1 (TSP-1) is highly expressed in response to inflammation. In this work, we isolated and identified human thymic mesenchymal stromal cells (tMSCs) and detected the expression of TSP-1. We found that tMSCs expressed TSP-1 and Poly (I:C) or...

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Identifiers

PMID: 34505627
DOI: 10.1042/BSR20203573
PMCID: PMC8521535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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