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Article

Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection.

PloS one - 1 Jan 2009

Caccamo Nadia, Guggino Giuliana, Meraviglia Serena, Gelsomino Giuseppe, Di Carlo Paola, Titone Lucina, Bocchino Marialuisa, Galati Domenico, Matarese Alessandro, Nouta Jan, Klein Michel R, Salerno Alfredo, Sanduzzi Alessandro, Dieli Francesco, Ottenhoff Tom H M

Abstract excerpt

CD8 T-cells contribute to control of Mycobacterium tuberculosis infection, but little is known about the quality of the CD8 T-cell response in subjects with latent infection and in patients with active tuberculosis disease. CD8 T-cells recognizing epitopes from 6 different proteins of Mycobacterium tuberculosis were detected by tetramer staining. Intracellular cytokines staining for specific production of...

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Share to CD8-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19436760
DOI: 10.1371/journal.pone.0005528
PMCID: PMC2678250

Genes

CCR7

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