Article
Increased activation and expansion of a CD57+ subset within peripheral CD8+ T lymphocytes in Mycobacterium tuberculosis-infected patients.
Archives of Iranian medicine - 1 Jan 2006
Fateminasab Farah-Dokht, Shahgasempour Shapour, Mirsaeidi Seyed-Mehdi, Tabarsi Payam, Mansoori Seyed-Davood, Entezami Zinat
Abstract excerpt
BACKGROUND: Mycobacterium tuberculosis-specific CD8+ and CD4+ T lymphocyte responses restrict the spread of extracellular pathogens by limiting M.tuberculosis replication. Alterations in cytolytic function, inappropriate maturation/differentiation, and limited proliferation could reduce their ability to control M.tuberculosis replication. METHODS: In an attempt to further characterize the immune responses during...
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