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Article

Role of CD8<sup>+</sup> T cells in mycobacterial infections

1 Aug 2000

Abstract excerpt

The interaction between IFN-gamma-secreting CD4+ T cells and macrophages has long been established as integral in the protective immune response against tuberculosis. More recently, evidence from murine experiments and human studies has begun to demonstrate an essential role for MHC class I restricted CD8+ T cells in this immune response. CD8+ T cells can produce the protective cytokines IFN-gamma and TNF-alpha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10947856
DOI: 10.1046/j.1440-1711.2000.00936.x

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