Article
Association of copy number variation across the genome with neuropsychiatric traits in the general population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2018
Guyatt Anna L, Stergiakouli Evie, Martin Joanna, Walters James, O'Donovan Michael, Owen Michael, Thapar Anita, Kirov George, Rodriguez Santiago, Rai Dheeraj, Zammit Stan, Gaunt Tom R
Abstract excerpt
Copy number variants (CNVs) are associated with psychiatric conditions in clinical populations. The relationship between rare CNV burden and neuropsychiatric traits in young, general populations is underexplored. A total of 6,807 children from the Avon Longitudinal Study of Parents and Children (ALSPAC) were studied. CNVs were inferred from single nucleotide polymorphism-array data using PennCNV. After excluding...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.