A genome-wide investigation of SNPs and CNVs in schizophrenia.

doi:10.1371/journal.pgen.1000373

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Article

A genome-wide investigation of SNPs and CNVs in schizophrenia.

PLoS genetics - 1 Feb 2009

Need Anna C, Ge Dongliang, Weale Michael E, Maia Jessica, Feng Sheng, Heinzen Erin L, Shianna Kevin V, Yoon Woohyun, Kasperaviciūte Dalia, Gennarelli Massimo, Strittmatter Warren J, Bonvicini Cristian, Rossi Giuseppe, Jayathilake Karu, Cola Philip A, McEvoy Joseph P, Keefe Richard S E, Fisher Elizabeth M C, St Jean Pamela L, Giegling Ina, Hartmann Annette M, Möller Hans-Jürgen, Ruppert Andreas, Fraser Gillian, Crombie Caroline, Middleton Lefkos T, St Clair David, Roses Allen D, Muglia Pierandrea, Francks Clyde, Rujescu Dan, Meltzer Herbert Y, Goldstein David B

Abstract excerpt

We report a genome-wide assessment of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) in schizophrenia. We investigated SNPs using 871 patients and 863 controls, following up the top hits in four independent cohorts comprising 1,460 patients and 12,995 controls, all of European origin. We found no genome-wide significant associations, nor could we provide support for any previously reported...

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PMID: 19197363
DOI: 10.1371/journal.pgen.1000373
PMCID: PMC2631150

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APBA2
NRXN1

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